PI31 is a proline-rich protein and its C-terminal region can act as a potent 20S proteasome inhibitor in vitro. In cells, it plays a role in regulating 26S proteasome assembly and activity.
Additional Information
Product Name: | 6xHis-PI31 |
Also Known As: | PSMF1 |
Catalog No.: | A3900 |
Size: | 25 µg |
Molecular Weight: | 29.8 kDa |
Species: | Human |
Source: | Bacterial recombinant |
Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
Concentration: | See tube label |
Quality Assurance: | ~85% by SDS-PAGE, see datasheet for gel image |
Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
PDF Data Sheet: | PDF Datasheet， MSDS |
NCBI RefSeq: | N/A |
Image(s): | N/A |
Shipping Method: | Dry ice shipping |
References: | 1. McCutchen-Maloney S., et all. (2000) J Biol Chem. 275(24):18557–185652. Cho-Park PF, et al. (2013) Cell 153(3):614-27 |
Details
PI31 is a proline-rich protein and its C-terminal region can act as a potent 20S proteasome inhibitor in vitro. In cells, it plays a role in regulating 26S proteasome assembly and activity.
