Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has been found to also process a ubiquitin-like substrate called NEDD8. It is 52% identical to the amino acid sequence of its related DUB, UchL1, and may share roles in maintaining neurons of the gracile tract in mice.
Additional Information
Product Name: | GST-UCHL3 |
Also Known As: | GST-UCH-L3 |
Catalog No.: | H1211 |
Size: | 100 µg |
Molecular Weight: | 26.2 kDa |
Species: | Human |
Source: | Bacterial recombinant |
Stock: | 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol |
Concentration: | See tube label |
Quality Assurance: | ~95% by SDS-PAGE, see datasheet for gel image |
Storage: | Store at -80°C; avoid multiple freeze-thaw cycles |
PDF Data Sheet: | PDF Datasheet， MSDS |
NCBI RefSeq: | NM_001270952 |
Image(s): | N/A |
Shipping Method: | Dry ice shipping |
References: | 1. Pckard CM, Rose IA (1985) J Biol Chem 260(13), 7903 – 7910.2. Day IN, et al. (1990) Biochem J 268(2), 521 – 524.3. Wilkinson KD, et al. (1999) J Mol Biol 291(5), 1067 – 1077.4. Kwon J (2007) Exp Anim 56(2), 71 – 77. |
Details
Ubiquitin C-terminal hydrolase L3 (UchL3) is a deubiquitinase enzyme (DUB), which performs hydrolysis of the bond at the C terminus of the ubiquitin and trims down the polyubiquitin chain into monomers. UchL3 has been found to also process a ubiquitin-like substrate called NEDD8. It is 52% identical to the amino acid sequence of its related DUB, UchL1, and may share roles in maintaining neurons of the gracile tract in mice.
