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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
ubpbio/AZD6738/F8140/5 mg
产品编号:F8140
市  场 价:¥2200.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$110.00
品      牌: UBPBio
公司分类:
ubpbio/AZD6738/F8140/5 mg
商品介绍
AZD6738 is a potent inhibitor of ATR kinase. It potentiates the cytotoxicity of cisplatin and gemcitabine in non-small cell lung cancer (NSCLC) cell lines with intact ATM kinase signaling, and potently synergizes with cisplatin in ATM-deficient NSCLC cells.

Additional Information

Product Name: AZD6738
Also Known As: 4-[4-[1-[[S(R)]-S-methylsulfonimidoyl]cyclopropyl]-6-[(3R)-3-methyl-4-morpholinyl]-2-pyrimidinyl]-1H-pyrrolo[2,3-b]pyridine
Catalog No.: F8140
Size: 5 mg
CAS: 1352226-88-0
Formula: C20H24N6O2S
Molecular Weight: 412.51 Da
Form: Lyophilized powder
Quality Assurance: >98% by HPLC and NMR
Source: Synthetic
Storage: Eligible for room temperature shipping. Store at -80°C upon receiving
PDF Data Sheet: Download PDF datasheet
Image(s): N/A
Shipping Method: Room temperature shipping
References: Vendetti FP, et al. (2015) Oncotarget. Oct 27.

Details

AZD6738 is a potent inhibitor of ATR kinase. It potentiates the cytotoxicity of cisplatin and gemcitabine in non-small cell lung cancer (NSCLC) cell lines with intact ATM kinase signaling, and potently synergizes with cisplatin in ATM-deficient NSCLC cells.

Solubility:
20 mg/ml in DMSO
品牌介绍

泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。 

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