BX-795isaninhibitorof3-phosphoinositide-dependentkinase1(PDK1),aswellasotherkinasesincludingTANK-bindingkinase1(TBK1),AuroraBandIkBkinaseε(IKKε).BX-795preventsTBK1-andIKKε-mediatedactivationofIRF3andproductionofIFN-β.
AdditionalInformation
| ProductName: | BX795 |
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| AlsoKnownAs: | N-(3-(5-iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide |
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| CatalogNo.: | F6150 |
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| Size: | 5mg |
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| CAS: | 702675-74-9 |
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| Formula: | C23H26IN7O2S |
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| MolecularWeight: | 591.47Da |
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| Form: | Lyophilizedpowder |
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| QualityAssurance: | >98%byHPLCandNMR |
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| Source: | Synthetic |
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| Storage: | EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving |
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| PDFDataSheet: | DownloadPDFdatasheet |
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| Image(s): | N/A |
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| ShippingMethod: | Roomtemperatureshipping |
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| References: | FeldmanRI,etal.(2005)J.Biol.Chem.28019867. |
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Details
BX-795isaninhibitorof3-phosphoinositide-dependentkinase1(PDK1),aswellasotherkinasesincludingTANK-bindingkinase1(TBK1),AuroraBandIkBkinaseε(IKKε).BX-795preventsTBK1-andIKKε-mediatedactivationofIRF3andproductionofIFN-β.
Solubility:
>20mg/mlinDMSO
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