BX-795isaninhibitorof3-phosphoinositide-dependentkinase1(PDK1),aswellasotherkinasesincludingTANK-bindingkinase1(TBK1),AuroraBandIkBkinaseε(IKKε).BX-795preventsTBK1-andIKKε-mediatedactivationofIRF3andproductionofIFN-β.
AdditionalInformation
ProductName: | BX795 |
---|
AlsoKnownAs: | N-(3-(5-iodo-4-(3-(thiophene-2-carboxamido)propylamino)pyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamide |
---|
CatalogNo.: | F6150 |
---|
Size: | 5mg |
---|
CAS: | 702675-74-9 |
---|
Formula: | C23H26IN7O2S |
---|
MolecularWeight: | 591.47Da |
---|
Form: | Lyophilizedpowder |
---|
QualityAssurance: | >98%byHPLCandNMR |
---|
Source: | Synthetic |
---|
Storage: | EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving |
---|
PDFDataSheet: | DownloadPDFdatasheet |
---|
Image(s): | N/A |
---|
ShippingMethod: | Roomtemperatureshipping |
---|
References: | FeldmanRI,etal.(2005)J.Biol.Chem.28019867. |
---|
Details
BX-795isaninhibitorof3-phosphoinositide-dependentkinase1(PDK1),aswellasotherkinasesincludingTANK-bindingkinase1(TBK1),AuroraBandIkBkinaseε(IKKε).BX-795preventsTBK1-andIKKε-mediatedactivationofIRF3andproductionofIFN-β.
Solubility:
>20mg/mlinDMSO
泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。