KU-60019isapotentATMkinaseinhibitor(IC50=6.3nM)incell-freeassays.Exhibitslittletonononspecifictargeteffectsagainstapanelof229proteinkinases,includingATRandDNA-PKcs.Itisahighlyeffectiver
ADIosensitizer.
AdditionalInformation
ProductName: | KU-60019 |
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AlsoKnownAs: | 2-((2S,6R)-2,6-dimethylmorpholino)-N-(5-(6-morpholino-4-oxo-4H-pyran-2-yl)-9H-thioxanthen-2-yl)acetamide |
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CatalogNo.: | F8120 |
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Size: | 5mg |
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CAS: | 925701-49-1 |
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Formula: | C30H33N3O5S |
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MolecularWeight: | 547.67Da |
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Form: | Lyophilizedpowder |
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QualityAssurance: | >98%byHPLCandNMR |
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Source: | Synthetic |
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Storage: | EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving |
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PDFDataSheet: | DownloadPDFdatasheet |
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Image(s): | N/A |
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ShippingMethod: | Roomtemperatureshipping |
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References: | GoldingSE,etal.(2009)MolCancerTher,8(10),2894-2902. |
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Details
KU-60019isapotentATMkinaseinhibitor(IC50=6.3nM)incell-freeassays.Exhibitslittletonononspecifictargeteffectsagainstapanelof229proteinkinases,includingATRandDNA-PKcs.Itisahighlyeffectiveradiosensitizer.
Solubility:
10mg/mlinDMSO
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