商品介绍
Rapamycinisanantifungalandimmunosuppressant.Rapamycinwasoriginallyusedanantifungalantibiotic.ItisnowknownasaspecificinhibitorofmTOR.RapamycinbindstoFK-bindingprotein12(FKBP12)andformstherapamycin-FKBP12complex,whichregulatesanenzymethatplaysanimportantroleintheprogressionofthecellcycle.RapamycinandotherinhibitorsofmTORC1signalingshowpotentialintreatingcancer,ADIpogenesis,diabetes,tuberoussclerosis,andcardiovasculardisease.
AdditionalInformation
| ProductName: | Rapamycin |
|---|---|
| AlsoKnownAs: | AY-22989,LCP-Siro,RAPA,Rapamune,Sirolimus,SILA9268A |
| CatalogNo.: | F6130 |
| Size: | 10mg |
| MolecularWeight: | 914.17Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >99%byHPLCandNMR |
| Storage: | EligIBLeforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
| PDFDataSheet: | PDFDatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | (Clickimagetoenlarge) PuritycheckofRapamycinbyHPLC |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.CorradettiMN,etal.(2006)Oncogene.25(48):6347-60. 2.FosterKG,etal.(2010)JBiolChem.285(19):14071-7. 3.MalageladaC,etal.(2010)JNeurosci.30(3):1166-75. |
