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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
ubpbio/b-AP15/F2101/10 mg
产品编号:F2101
市  场 价:¥2700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$135.00
品      牌: UBPBio
公司分类:
ubpbio/b-AP15/F2101/10 mg
商品介绍
b-AP15isaspecificinhibitorofthedeubiquitinatingenzymesUch37andUSP14ofthe26Sproteasome.Itblocksthedeubiquitinatingactivityofthe26Sproteasome.Treatingcellswithb-AP15causestheaccumulationofpolyubiquitinatedproteins,inhibitionofproteasomaldegradation,upregulationofapoptoticMarkersandcelldeath.

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b-AP15isaspecificinhibitorofthedeubiquitinatingenzymesUch37andUsp14ofthe26Sproteasome.Itblocksthedeubiquitinatingactivityofthe26Sproteasome.Treatingcellswithb-AP15causestheaccumulationofpolyubiquitinatedproteins,inhibitionofproteasomaldegradation,upregulationofapoptoticmarkersandcelldeath.

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EqualamountofwholecelllysatespreparedfromDMSO(lane1)or2μMb-AP15(lane2)-treatedHeLacellswereseparatedbySDS-PAGEandimmunoblottedwithananti-Ubantibody.HEK293TCellsweretreatedwithDMSOorb-AP15for5hours.
品牌介绍

泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。 

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ProductName:b-AP15
AlsoKnownAs:No
CatalogNo.:F2101
Size:10mg
MolecularWeight:419.4Da
Species:N/A
Source:Synthetic
Stock:Powder
Concentration:N/A
QualityAssurance:>98%byHPLCandNMR
Storage:EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving;avoidmultiplefreeze-thawcyclesafterdissolvinginDMSO.
PDFDataSheet:DownloadPDFdatasheet
NCBIRefSeq:N/A
Image(s):No
ShippingMethod:Roomtemperatureshipping
References:1.D’AcryP,etal.(2011)Nat.Med.17.1636.