商品介绍
Ixazomib(MLN2238)(commercialname:Ninlaro®)isthefirstandonlyFDA-approvedoralproteasomeinhibitorforthetreatmentofmultiplemyeloma.ItreversIBLyinhibitsthechymotrypsin-likeactivityofproteasomeswithIC50of3.4nMincell-freeassays,alsoinhibitsthecaspase-likeandtrypsin-likeactivitiesofproteasomewithIC50of31and3500nM,respectively.
AdditionalInformation
| ProductName: | Ixazomib(MLN-2238) |
|---|---|
| AlsoKnownAs: | [(1R)-1-[[(2S,3R)-3-hydroxy-2-[(6-phenylpyridine-2-carbonyl)amino]butanoyl]amino]-3-methylbutyl]boronicacid |
| CatalogNo.: | F1111 |
| Size: | 25mg |
| CAS: | 1072833-77-2 |
| Formula: | C14H19BCl2N2O4 |
| MolecularWeight: | 361.03Da |
| Form: | Lyophilizedpowder |
| QualityAssurance: | >98%byHPLCandNMR |
| Source: | Synthetic |
| Storage: | Eligibleforroomtemperatureshipping.Storeat-80°Cuponreceiving |
| PDFDataSheet: | DownloadPDFdatasheet |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | N/A |
