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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
ubpbio/UBE1/B1100/25 µg
产品编号:B1100
市  场 价:¥2400.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$120.00
品      牌: UBPBio
公司分类:
ubpbio/UBE1/B1100/25 µg
商品介绍
UBE1isanE1enzymewithintheE1,E2,E3cascadewhichconjugatesUbtoproteinsubstrates.UBE1activatesUbbycatalyzinganATP–dependentreaction;UbisconjugatedontothecatalyticCysresidueofUBE1byformationofathioesterbond.TheactivatedUbisthenpassedontoaUb-conjugatingenzymeE2;UbchargedE2bindsaUbligaseE3thatdirectlybindssubstrateproteins.UbistransferredtotheHECTdomainE3spriortobeingconjugatedonsubstrateproteins.ForRINGdomainE3s,UbistransferreddirectlyfromanE2tosubstrateproteins.

AdditionalInformation

Details

UBE1isanE1enzymewithintheE1,E2,E3cascadewhichconjugatesUbtoproteinsubstrates.UBE1activatesUbbycatalyzinganATP–dependentreaction;UbisconjugatedontothecatalyticcysteineresidueofUBE1byformationofathioesterbond.TheactivatedUbisthenpassedontoaUb-conjugatingenzymeE2;UbchargedE2bindsaUbligaseE3thatdirectlybindssubstrateproteins.UbistransferredtotheHECTdomainE3spriortobeingconjugatedonsubstrateproteins.ForRINGdomainE3s,UbistransferreddirectlyfromanE2tosubstrateproteins.
Images:(Clickimagetoenlarge)
ProductName:UBE1
AlsoKnownAs:UBA1;A1S9;A1ST;GXP1;UBE1;A1S9T;AMCX1;POC20;SMAX2;UBA1A;UBE1X
CatalogNo.:B1100
Size:25µg
MolecularWeight:117.8kDa
Species:Human
Source:Sf21insectcells
Stock:20mMTris,150mMNaCl,2mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:~95%bySDS-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheetMSDS
NCBIRefSeq:NM_003334
Image(s):(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkers
Lane2:5µgpurifiedUBE1
ShippingMethod:Dryiceshipping
References:1.HandleyPM,etal.(1991)ProcNatlAcadSciUSA88,258–262.
2.ZhengM,etal.(2009)MolBiolRep37,1413–1419.3.SchulmanBA,etal.(2009)NatRevMolBiol10(5),319–331.
Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurifiedUBE1
品牌介绍

泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。 

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