ubpbio/Bovine 26S proteasome/A1200/25 µg,UBPBio,,UBPBio,Ubiquitin-Proteasome Biotechnologies,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：ubpbio/Bovine 26S proteasome/A1200/25 µg

产品编号：A1200

市场价：¥4800.00

场地：美国(厂家直采)

产品分类：蛋白类>酶>蛋白酶类>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$240.00

品牌： UBPBio

公司：Ubiquitin-Proteasome Biotechnologies, LLC

公司分类：

商品介绍

The26Sproteasomeisanapproximately2.5mDalargecomplexcomposedofthe20Sproteasomeandthe19Sregulatoryparticle(alsocalledPA700inmammals).The20Sproteasomehas28subunitsthatformabarrel–shapedstructurearrangedasfourheptomericringofαββα.Threeβsubunitshavepeptidaseactivitiesthathydrolyzeproteins.Eitheroneorbothendsofthe20SproteasomecanassociatewithPA700toformthe26Sproteasome.PA700contains19differentproteinsthathavetheABIlitytobind,deubiquitinateandunfoldpolyubiquitinatedproteinswiththeconsumptionofATPhydrolysis.The26Sproteasomedegradespolyubiquitinatedproteins,whichplaysessentialrolesinregulatingvariouscellulareventsincludingproteinqualitycontrol,genetranscriptionandsignaltransduction.

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Details

The26Sproteasomeisanapproximately2.5mDalargecomplexcomposedofthe20Sproteasomeandthe19Sregulatoryparticle(alsocalledPA700inmammals).The20Sproteasomehas28subunitsthatformabarrel–shapedstructurearrangedasfourheptomericringofαββα.Threeβsubunitshavepeptidaseactivitiesthathydrolyzeproteins.Eitheroneorbothendsofthe20SproteasomecanassociatewithPA700toformthe26Sproteasome.PA700contains19differentproteinsthathavetheabilitytobind,deubiquitinateandunfoldpolyubiquitinatedproteinswiththeconsumptionofATPhydrolysis.The26Sproteasomedegradespolyubiquitinatedproteins,whichplaysessentialrolesinregulatingvariouscellulareventsincludingproteinqualitycontrol,genetranscriptionandsignaltransduction.

Images
(Clickimagetoenlarge)

ProductName:

Bovine26Sproteasome

AlsoKnownAs:

26Sproteasome

CatalogNo.:

A1200

Size:

25µg

MolecularWeight:

~2500kDa

Species:

Bovine

Source:

Bovineredbloodcells

Stock:

20mMTris,pH7.6,40mMNaCl,2mMβME,2mMATP,5mMMgCl₂,10%Glycerol

Concentration:

Seetubelabel

QualityAssurance:

Atleast90%bynative-PAGE,seedatasheetforgelimage

Storage:

Storeat-80°C;avoidmultiplefreeze-thawcycles

PDFDataSheet:

PDFDatasheet，MSDS

NCBIRefSeq:

N/A

Image(s):

(Clickimagetoenlarge)

Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkers
Lane2:5µgpurifiedBovine26Sproteasome

3µgpurifiedbovine26Sproteasomewasresolvedby4%native-PAGE.TheproteinwasvisualizedbyCoomassie-staining(lane1);ortheproteasomeactivitywasdeterminedbyanoverlayassayusingSuc-LLVY-AMCasthesubstrate(lane2).

ShippingMethod:

Dryiceshipping

References:

1.WaxmanL,etal.(1987)JBiolChem262(6),2451–2457.
2.PickartCM(1997)FASEBJ11(13),1055–1066.3.XieY(2010)JMolCellBiol2(6),308–317.

Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurifiedBovine26Sproteasome

品牌介绍

泛素-蛋白酶体生物技术有限公司（UBPBio），LLC是一家私有公司，由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂，以加快对泛素-蛋白酶体系统及相关途径的发现。。目前，我们的产品线包括16个类别，提供350多种产品。如果您在泛素领域需要特殊试剂，请与我们联系，我们将竭诚为您服务。

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