hHR23AandhHR23BarethehumanhomologuesofyeastRad23.Rad23caninteractwiththeRpn10andRpn1subunitsofthe26SproteasomeviaitsN-terminalUb-likedomain(UBL).Rad23alsocontainstwoUb-associateddomains(UBA),throughwhichitbindspolyubiquitinatedproteinsforproteasomaldegradation.Inaddition,Rad23canalsobindDNArepairfactorstoregulatenucleotideexcisionrepairfromUVdamage.
AdditionalInformation
ProductName: | GST-hHR23B(Rad23B) |
---|
AlsoKnownAs: | P58;HR23B;HHR23B |
---|
CatalogNo.: | I1111 |
---|
Size: | 100µg |
---|
MolecularWeight: | 43.2kDa |
---|
Species: | Human |
---|
Source: | Bacterialrecombinant |
---|
Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
---|
Concentration: | Seetubelabel |
---|
QualityAssurance: | ~90%bySDS-PAGE,seedatasheetforgelimage |
---|
Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
---|
PDFDataSheet: | PDFDatasheet,MSDS |
---|
NCBIRefSeq: | NM_002874 |
---|
Image(s): | No |
---|
ShippingMethod: | Dryiceshipping |
---|
References: | 1.WatkinsJF,etal.(1993)MolCellBiol13(12),7757–7765. 2.ChenL,etal.(2002)MolCellBiol22(13),4902–4913.3.WadeSL,etal.(2010)Transcription1,22–26. |
---|
Details
hHR23AandhHR23BarethehumanhomologuesofyeastRad23.Rad23caninteractwiththeRpn10andRpn1subunitsofthe26SproteasomeviaitsN-terminalUb-likedomain(UBL).Rad23alsocontainstwoUb-associateddomains(UBA),throughwhichitbindspolyubiquitinatedproteinsforproteasomaldegradation.Inaddition,Rad23canalsobindDNArepairfactorstoregulatenucleotideexcisionrepairfromUVdamage.
泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。