hHR23AandhHR23BarethehumanhomologuesofyeastRad23.Rad23caninteractwiththeRpn10andRpn1subunitsofthe26SproteasomeviaitsN-terminalUb-likedomain(UBL).Rad23alsocontainstwoUb-associateddomains(UBA),throughwhichitbindspolyubiquitinatedproteinsforproteasomaldegradation.Inaddition,Rad23canalsobindDNArepairfactorstoregulatenucleotideexcisionrepairfromUVdamage.
AdditionalInformation
| ProductName: | GST-hHR23B(Rad23B) |
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| AlsoKnownAs: | P58;HR23B;HHR23B |
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| CatalogNo.: | I1111 |
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| Size: | 100µg |
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| MolecularWeight: | 43.2kDa |
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| Species: | Human |
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| Source: | Bacterialrecombinant |
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| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
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| Concentration: | Seetubelabel |
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| QualityAssurance: | ~90%bySDS-PAGE,seedatasheetforgelimage |
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| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
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| PDFDataSheet: | PDFDatasheet,MSDS |
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| NCBIRefSeq: | NM_002874 |
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| Image(s): | No |
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| ShippingMethod: | Dryiceshipping |
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| References: | 1.WatkinsJF,etal.(1993)MolCellBiol13(12),7757–7765. 2.ChenL,etal.(2002)MolCellBiol22(13),4902–4913.3.WadeSL,etal.(2010)Transcription1,22–26. |
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Details
hHR23AandhHR23BarethehumanhomologuesofyeastRad23.Rad23caninteractwiththeRpn10andRpn1subunitsofthe26SproteasomeviaitsN-terminalUb-likedomain(UBL).Rad23alsocontainstwoUb-associateddomains(UBA),throughwhichitbindspolyubiquitinatedproteinsforproteasomaldegradation.Inaddition,Rad23canalsobindDNArepairfactorstoregulatenucleotideexcisionrepairfromUVdamage.
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