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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
ubpbio/VE-821/F8131/25 mg
产品编号:F8131
市  场 价:¥4000.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$200.00
品      牌: UBPBio
公司分类:
ubpbio/VE-821/F8131/25 mg
商品介绍
VE-821isapotentandselectiveATPcompetitiveinhibitorofataxia-telangiectasiaandRad3-relatedprotein(ATR)withIC50of26nMincell-freeassays,withminimalactivityagainstATM,DNA-PK,andmTOR.ItaugmentsDNAdamageandcelldeathofcancercellsinresponsetorADIation,alsosensitizescancercellstochemotherapy.

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Details

VE-821isapotentandselectiveATPcompetitiveinhibitorofataxia-telangiectasiaandRad3-relatedprotein(ATR)withIC50of26nMincell-freeassays,withminimalactivityagainstATM,DNA-PK,andmTOR.ItaugmentsDNAdamageandcelldeathofcancercellsinresponsetoradiation,alsosensitizescancercellstochemotherapy.

Solubility:
20mg/mlinDMSO
品牌介绍

泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。 

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ProductName:VE-821
AlsoKnownAs:3-Amino-6-[4-(methylsulfonyl)phenyl]-N-phenyl-2-pyrazinecarboxamide
CatalogNo.:F8131
Size:25mg
CAS:1232410-49-9
Formula:C18H16N4O3S
MolecularWeight:368.41Da
Form:Lyophilizedpowder
QualityAssurance:>98%byHPLCandNMR
Source:Synthetic
Storage:EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving
PDFDataSheet:DownloadPDFdatasheet
Image(s):N/A
ShippingMethod:Roomtemperatureshipping
References:1.ReaperPM,etal.(2011)NatChemBiol,7(7),428-430.
2.Prevo,R,etal.(2012)CancerBiolTher,13(11)1072-1081.
3.Huntoon,CJ,etal.(2013)CancerRes,73(12)3683-3691.