商品介绍
DoxorubicinisananthracyclineantitumorantibioticthatInducesDNAdamagebyintercalatingintoDNAandinhibitingtopoisomeraseII.DoxorubicinbindscovalentlytoDNAandinhbibitsreversetranscriptase,RNApolymeraseandthecatalyticactivityofDnmt1.
AdditionalInformation
| ProductName: | DoxorubicinHCl |
|---|---|
| AlsoKnownAs: | 10-[(3-Amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-5,12-naphthacenedionehydrochloride |
| CatalogNo.: | F8111 |
| Size: | 25mg |
| MolecularWeight: | 579.99Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >99%byHPLCandNMR |
| Storage: | EligIBLeforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
| PDFDataSheet: | PDFDatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.TAATjesDJ,etal(1996)J.Med.Chem.39:4135-4138. 2.PourquierP,etal.(1998)Biochem.Pharmacol.55:1963-1971. 3.ZemanSM,etal.(1998)Proc.Natl.Acad.Sci.U.S.A.95:11561-11565. 4.SunW,etal.(2009)CancerRes.69(10):4294-4300. 5.Granados-PrincipalS,etal.(2010)FoodChemToxicol48(6):1425-1438. |
