商品介绍
AT-406(alsocalledSM-406)isapotentSmacmimeticthatinhibitstheubiquitinligaseactivityofinhibitorsofapoptosisproteinsXIAP,cIAP1andcIAP2withKivaluesof66.4,1.9and5.1nM,respectively.AT-406inducesapoptosisofvarioushumancancercelllines.
AdditionalInformation
| ProductName: | AT-406(SM-406) |
|---|---|
| AlsoKnownAs: | CAS#1071992-99-8 |
| CatalogNo.: | F7170-25 |
| Size: | 25mg |
| MolecularWeight: | 561.71Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >98%byHPLCandNMR |
| Storage: | EligIBLeforroomtemperatureshipping.Storeat-80°Cuponreceiving;avoidmultiplefreeze-thawcyclesafterdissolvinginDMSO. |
| PDFDataSheet: | DownloadPDFdatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | No |
| ShippingMethod: | Roomtemperatureshipping |
| References: | 1.CaiQ.,etal.(2011)J.Med.Chem.54,2714 2.BrunckhorstM.K.,etal.(2012)CancerBiol.Ther.,13,804 |
