商品介绍
Pifithrin-alphaisaninhibitorofp53,reversIBLyinhibitsp53-dependenttransactivationofp53-responsivegenesandapoptosis.Pifithrin-α(10μM)enhancescellsurvivalaftergenotoxicstresssuchasUVirrADIationandtreatmentwithDNAdamagecompoundsincludingdoxorubicin,etopoxide,andpaclitaxel.
AdditionalInformation
| ProductName: | Pifithrin-alpha |
|---|---|
| AlsoKnownAs: | Pifithrin-α,Ethanone,1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-,hydrobromide(1:1) |
| CatalogNo.: | F7161 |
| Size: | 25mg |
| CAS: | 63208-82-2 |
| Formula: | C16H18N2OS.HBr |
| MolecularWeight: | 367.3Da |
| Form: | Lyophilizedpowder |
| QualityAssurance: | >98%byHPLCandNMR |
| Source: | Synthetic |
| Storage: | Eligibleforroomtemperatureshipping.Storeat-80°Cuponreceiving |
| PDFDataSheet: | DownloadPDFdatasheet |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | Komarov,PG,etal.(1999)Science285,1733-1737 |
