商品介绍
PYR-41isacell-permeable,irreversIBLeubiquitin-activatingenzyme(E1)inhibitor(IC50<10=""μm).=""treatment=""of=""cells=""with=""pyr-41=""inhibits=""overall=""protein=""ubiquitination,=""prevents=""ubiquitin-mediated=""proteasomal=""degradation,=""and=""inhibits=""pathways=""mediated=""by=""the=""ubiquitin-proteasome.=""it=""has=""also=""been=""found=""that=""pyr-41=""treatment=""increases=""protein=""sumoylation=""in="">
AdditionalInformation
| ProductName: | PYR-41 |
|---|---|
| AlsoKnownAs: | 4[4-(5-Nitro-furan-2-ylmethylene)-3,5-dioxo-pyrazolidin-1-yl]-benzoicacidethylester |
| CatalogNo.: | F5100 |
| Size: | 5mg |
| MolecularWeight: | 371.3Da |
| Species: | N/A |
| Source: | Synthetic |
| Stock: | Powder |
| Concentration: | N/A |
| QualityAssurance: | >98%(TLC);NMR(Confirms) |
| Storage: | Eligibleforroomtemperatureshipping.Storeat-20°Cuponreceiving;protectfromairandlight |
| PDFDataSheet: | PDFDatasheet |
| NCBIRefSeq: | N/A |
| Image(s): | N/A |
| ShippingMethod: | Roomtemperatureshipping |
| References: | Yang,Y.,etal.(2007)CancerRes.67:9472. |
