商品介绍
Deubiquitinatingenzymes(DUBs)areproteasesthatpossestheABIlitytocleaveubiquitinchainsortheisopeptidebondthatconjugatesubiquitinwithasubstrate.Humancellshaveapproximately100DUBsthatplayimportantrolesinregulatingvariouscellularevents.A20downregulatestheNF-κBpathwayandproinflammatorygeneexpressionincellssuchasmacrophages.TheN-terminaldomainofA20containstheDUBactivity.
AdditionalInformation
| ProductName: | GST-A20(1-365) |
|---|---|
| AlsoKnownAs: | TNFAIP3;OTUD7C;TNFA1P2 |
| CatalogNo.: | H3210 |
| Size: | 25µg |
| MolecularWeight: | 89.6kDa |
| Species: | Human |
| Source: | Bacterialrecombinant |
| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
| Concentration: | Seetubelabel |
| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
| PDFDataSheet: | PDFDatasheet，MSDS |
| NCBIRefSeq: | NM_006290 |
| Image(s): | N/A |
| ShippingMethod: | Dryiceshipping |
| References: | 1.OpipariAWJr,etal.(1990)JBiolChem265(25),14705–14708. 2.BooneDL,etal.(2004)NatImmunol5(10),1052–1060. |
