UbiquitinC-terminalhydrolaseL3(UchL3)isadeubiquitinaseenzyme(DUB),whichperformshydrolysisofthebondattheCterminusoftheubiquitinandtrimsdownthepolyubiquitinchainintomonomers.UchL3hasbeenfoundtoalsoprocessaubiquitin-likesubstratecalledNEDD8.Itis52%identicaltotheaminoacidsequenceofitsrelatedDUB,UchL1,andmaysharerolesinmaintainingneuronsofthegraciletractinmice.
AdditionalInformation
| ProductName: | GST-UCHL3 |
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| AlsoKnownAs: | GST-UCH-L3 |
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| CatalogNo.: | H1211 |
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| Size: | 100µg |
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| MolecularWeight: | 26.2kDa |
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| Species: | Human |
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| Source: | Bacterialrecombinant |
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| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
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| Concentration: | Seetubelabel |
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| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
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| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
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| PDFDataSheet: | PDFDatasheet,MSDS |
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| NCBIRefSeq: | NM_001270952 |
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| Image(s): | N/A |
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| ShippingMethod: | Dryiceshipping |
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| References: | 1.PckardCM,RoseIA(1985)JBiolChem260(13),7903–7910. 2.DayIN,etal.(1990)BiochemJ268(2),521–524.3.WilkinsonKD,etal.(1999)JMolBiol291(5),1067–1077. 4.KwonJ(2007)ExpAnim56(2),71–77. |
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Details
UbiquitinC-terminalhydrolaseL3(UchL3)isadeubiquitinaseenzyme(DUB),whichperformshydrolysisofthebondattheCterminusoftheubiquitinandtrimsdownthepolyubiquitinchainintomonomers.UchL3hasbeenfoundtoalsoprocessaubiquitin-likesubstratecalledNEDD8.Itis52%identicaltotheaminoacidsequenceofitsrelatedDUB,UchL1,andmaysharerolesinmaintainingneuronsofthegraciletractinmice.
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