商品介绍
UbchainsareformedbyconjugatingtheC-terminalglycineresidueofUbontoanyofseveninternallysineresiduesortheaminogroupofthepreviousUb.UbchainsareclassifiedbythelysineresidueusedtolinkUbs;differentUbchaintopologiescanresultindifferentsignals.Forinstance,Ubchainslinkedthroughlysine6,11,27,29,33and48arecapableoftargetingproteinsforproteasomaldegradation;incontrast,Ubchainslinkedthroughlysine63ortheN-terminalaminogroup(linearUbchains)oftenplayimportantnonproteolyticfunctionsincludingregulationofkinaseactivationandproteintranslation.AllUbchainproductsareproducedbyusingofhumanwildtypeUbreactingwithspecificE2s.
AdditionalInformation
| ProductName: | K63-Ub4 |
|---|---|
| AlsoKnownAs: | K63-Ub4 |
| CatalogNo.: | D2301 |
| Size: | 50µg |
| MolecularWeight: | 33.1kDa |
| Species: | Human |
| Source: | Bacterialrecombinant |
| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
| Concentration: | Seetubelabel |
| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
| PDFDataSheet: | PDFDatasheet，MSDS |
| NCBIRefSeq: | N/A |
| Image(s): | N/A |
| ShippingMethod: | Dryiceshipping |
| References: | 1.HershkoA,etal.(1980)ProcNatlAcadSciUSA77(4),1783–1786. 2.PickartCM,(1997)FASEB11(13),1055–1066.3.HershkoA,etal.(1998)AnnRevBiochem67,425–479. 4.JiangX,etal.(2012)NatureReviewsImmunology12,35–48. |
