| ProductName: | GST-NEDD4 |
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| AlsoKnownAs: | NEDD4-1;neuralprecursorcellexpresseddevelopmentallydown-regulatedprotein4 |
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| CatalogNo.: | K1420 |
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| Size: | 50µg |
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| MolecularWeight: | 104kDa(noGSTtag) |
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| Species: | Human |
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| Source: | Bacterialrecombinant |
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| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
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| Concentration: | Seetubelabel |
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| QualityAssurance: | ~90%bySDS-PAGE,seedatasheetforgelimage |
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| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
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| PDFDataSheet: | PDFDatasheet |
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| NCBIRefSeq: | NM_006154.3 |
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| Image(s): | (Clickimagetoenlarge)
 | Coomassie-stainedSDS-PAGE Lane1:MolecularweightMarkers Lane2:5µgpurifiedGST-UbE3A(E6AP)
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| ShippingMethod: | Dryiceshipping |
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| References: | 1.CaoXR,etal.,NEDD4controlsanimalgrowthbyregulatingIGF-1signaling.SciSignal.1(38):ra5.2.WangX,etal.,NEDD4-1isaproto-oncogenicubiquitinligaseforPTEN.Cell.128,129. |
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NEDD4(neuralprecursorcellexpresseddevelopmentallydown-regulatedprotein4)isawidelyexpressedHECTdomain-containingE3ubiquitinligase.NEDD4ubiquitinatesafewmembraneproteins,includingIGF-1RandPTEN,bywhichitregulatessignaltransduction.
Images:(Clickimagetoenlarge)