ubpbio/ITCH/K1400/50 µg,UBPBio,,UBPBio,Ubiquitin-Proteasome Biotechnologies,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：ubpbio/ITCH/K1400/50 µg

产品编号：K1400

市场价：¥4300.00

场地：美国(厂家直采)

产品分类：分子类>核酸酶类>连接酶>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$215.00

品牌： UBPBio

公司：Ubiquitin-Proteasome Biotechnologies, LLC

公司分类：

商品介绍

ITCH,alsocalledatrophin-1interactingprotein4(AIP4),isaHECT-typeE3ubiquitinligase.ItcontainsanN-terminalCa<>-dependentphospholipid-bindingC2domain,fourWWdomains,andaC-terminalHECTdomain.MicedeficientinITCHproteindisplaymanyautoimmune-likediseasecharacteristicssuchaslymphoproliferationinthespleenandlymphnodes.MorethanadozenofsubstratesofITCHhavebeenidentifiedincludingp63,p73andNotch1.TheligasemayberesponsIBLeforubiquitinatingproteinswithK29-,K48-,and/orK63-linkedubiquitinchains.

AdditionalInformation

Details

ITCH,alsocalledatrophin-1interactingprotein4(AIP4),isaHECT-typeE3ubiquitinligase.ItcontainsanN-terminalCa<>-dependentphospholipid-bindingC2domain,fourWWdomains,andaC-terminalHECTdomain.MicedeficientinITCHproteindisplaymanyautoimmune-likediseasecharacteristicssuchaslymphoproliferationinthespleenandlymphnodes.MorethanadozenofsubstratesofITCHhavebeenidentifiedincludingp63,p73andNotch1.TheligasemayberesponsibleforubiquitinatingproteinswithK29-,K48-,and/orK63-linkedubiquitinchains.<>
Images:(Clickimagetoenlarge)

ProductName:

ITCH

AlsoKnownAs:

AIF4;AIP4;NAPP1;dJ468O1.1

CatalogNo.:

K1400

Size:

50µg

MolecularWeight:

102.8kDa

Species:

Human

Source:

Bacterialrecombinant

Stock:

20mMTris,150mMNaCl,2mMβME,10%Glycerol

Concentration:

Seetubelabel

QualityAssurance:

~90%bySDS-PAGE,seedatasheetforgelimage

Storage:

Storeat-80°C;avoidmultiplefreeze-thawcycles

PDFDataSheet:

PDFDatasheet，MSDS

NCBIRefSeq:

NM_001257137

Image(s):

(Clickimagetoenlarge)

Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkers
Lane2:5µgpurifiedITCH

ShippingMethod:

Dryiceshipping

References:

1.PerryWL,etal.(1998)NatGenet18,143–146.
2.SchwarzSE,etal.(1998)JBiolChem273,12148–12154.3.MelinoG,etal.(2008)CellDeathDiffer15(7),1103–1112.

Coomassie-stainedSDS-PAGE
Lane1:Molecularweightmarkers
Lane2:5µgpurifiedITCH

品牌介绍

泛素-蛋白酶体生物技术有限公司（UBPBio），LLC是一家私有公司，由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂，以加快对泛素-蛋白酶体系统及相关途径的发现。。目前，我们的产品线包括16个类别，提供350多种产品。如果您在泛素领域需要特殊试剂，请与我们联系，我们将竭诚为您服务。

公司介绍

更多...

产品分类

更多...