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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
ubpbio/6xHis-Ube2T/C3801/100 µg
产品编号:C3801
市  场 价:¥4200.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
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电话号码:4000-520-616
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美  元  价:$210.00
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ubpbio/6xHis-Ube2T/C3801/100 µg
商品介绍
Ube2T is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2T interacts with the E3 ligase called Fanconi anemia complementation group L (FANCL) that is part of a larger complex to regulate DNA damage repair. Once FANCL interacts with Ube2T, the complex is then able to monoubiquitinate FANCD2 that leads to the DNA repair. Ube2T can also interact with the BRCA1/BARD1 complex. PIG50; HSPC150

Additional Information

Product Name: 6xHis-Ube2T
Also Known As: PIG50; HSPC150
Catalog No.: C3801
Size: 100 µg
Molecular Weight: 22.5 kDa
Species: Human
Source: Bacterial recombinant
Stock: 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Concentration: See tube label
Quality Assurance: ~90% by SDS-PAGE, see datasheet for gel image
Storage: Store at -80°C; avoid multiple freeze-thaw cycles
PDF Data Sheet: PDF DatasheetMSDS
NCBI RefSeq: NM_014176
Image(s): (Click image to enlarge)
Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified 6xHis-Ube2T
Shipping Method: Dry ice shipping
References: 1. Zhang QH, et al. (2000) Genome Res 10, 1546 – 1560.
2. Machida YJ, et al. (2006) Mol Cell 23, 589-96.
3. Hao J, et al. (2008) Tumour Biol 29, 195 – 203.
4. Ueki T, et al. (2009) Cancer Res 69(22), 8752 – 8760.

Details

Ube2T is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. Ube2T interacts with the E3 ligase called Fanconi anemia complementation group L (FANCL) that is part of a larger complex to regulate DNA damage repair. Once FANCL interacts with Ube2T, the complex is then able to monoubiquitinate FANCD2 that leads to the DNA repair. Ube2T can also interact with the BRCA1/BARD1 complex.
Images:
(Click image to enlarge)
Coomassie-stained SDS-PAGE
Lane 1: Molecular weight markers
Lane 2: 5 µg purified 6xHis-Ube2T
品牌介绍

泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。 

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