Uch37isoneofthedeubiquitinatingenzymesofthehuman26Sproteasome,belongstotheUbC-terminalhydrolases.Uch37wasfoundtobindbothAdrm1andS5asubunitsofthe26Sproteasome.Uch37likelycontributestotheUbchaintrimmingactivityofthe26SproteasomethatshortensapolyUbchainfromthedistalendofthechain.
AdditionalInformation
| ProductName: | 6xHis-Uch37 |
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| AlsoKnownAs: | UCHL5;UCH37;CGI-70;INO80R;UCH-L5 |
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| CatalogNo.: | A3500 |
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| Size: | 25µg |
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| MolecularWeight: | 37.6kDa |
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| Species: | Human |
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| Source: | Bacterialrecombinant |
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| Stock: | 20mMTris,150mMNaCl,2mMβME,10%Glycerol |
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| Concentration: | Seetubelabel |
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| QualityAssurance: | ~95%bySDS-PAGE,seedatasheetforgelimage |
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| Storage: | Storeat-80°C;avoidmultiplefreeze-thawcycles |
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| PDFDataSheet: | PDFDatasheet,MSDS |
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| NCBIRefSeq: | NM_015984 |
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| Image(s): | No |
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| ShippingMethod: | Dryiceshipping |
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| References: | 1.VermaR,etal.(2000)MolBiolCell11(10),3425–3439. 2.KoulichE,etal.(2007)MolBiolCell,19(3)1072–1082.3.HusnjakK,etal.(2008)Nature453,481–488. 4.LeeBH,etal.(2010)Nature467,179–184. |
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Details
Uch37isoneofthedeubiquitinatingenzymesofthehuman26Sproteasome,belongstotheUbC-terminalhydrolases.Uch37wasfoundtobindbothAdrm1andS5asubunitsofthe26Sproteasome.Uch37likelycontributestotheUbchaintrimmingactivityofthe26SproteasomethatshortensapolyUbchainfromthedistalendofthechain.
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