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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
ubpbio/Bovine 19S (PA700)/A1300/25 µg
产品编号:A1300
市  场 价:¥5000.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
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美  元  价:$250.00
品      牌: UBPBio
公司分类:
ubpbio/Bovine 19S (PA700)/A1300/25 µg
商品介绍
The19Sregulatoryparticle(PA700)locatesoneitheroneorbothendsofthe20Scoreparticleofthe26Sproteasome.Ithas19subunitsincludingsixAAAATPasesthatassociatewithαsubunitsofthe20Sproteasometoformthe26Sproteasome.PA700playsanessentialroleinpreparingsubstrateproteinstobedegradedbythe20Sproteasome,includingbinding,deubiquitinatingandunfoldingpolyubiquitinatedproteins.

AdditionalInformation

Details

The19Sregulatoryparticle(PA700)locatesoneitheroneorbothendsofthe20Scoreparticleofthe26Sproteasome.Ithas19subunitsincludingsixAAAATPasesthatassociatewithαsubunitsofthe20Sproteasometoformthe26Sproteasome.PA700playsanessentialroleinpreparingsubstrateproteinstobedegradedbythe20Sproteasome,includingbinding,deubiquitinatingandunfoldingpolyubiquitinatedproteins.
Images(Clickimagetoenlarge)
ProductName:Bovine19S(PA700)
AlsoKnownAs:No
CatalogNo.:A1300
Size:25µg
MolecularWeight:900kDa
Species:Bovine
Source:Bovineredbloodcells
Stock:20mMTris,20mMNaCl,ImMEDTA,5mMβME,10%Glycerol
Concentration:Seetubelabel
QualityAssurance:Atleast90%bynative-PAGE,seedatasheetforgelimage
Storage:Storeat-80°C;avoidmultiplefreeze-thawcycles
PDFDataSheet:PDFDatasheetMSDS
NCBIRefSeq:N/A
Image(s):(Clickimagetoenlarge)
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightMarkersLane2:5µgpurifiedBovine19S(PA700)

Coomassie-stainednative-PAGE
Lane1:5µgpurifiedBovine19S(PA700)

Activationof5nM20Sproteasome(Cat.#A1400)by25nMPA700,theproteasomeactivitywasassayedbyusing50µMSuc-LLVY-AMC(Cat.#G1100)asthesubstrate.TheAMCfluorescencewasmonitoredbyaplatereaderwithexcitationandemissionfiltersof360±40nmand460±30nm,respectively.
ShippingMethod:Dryiceshipping
References:1.WaxmanL,etal.(1987)JBiolChem262(6),2451–2457.
2.KanayamaHO,etal.(1992)EurJBiochem206(2),567–578.3.GlickmanMH,etal.(1998)Cell94,615–623.
4.DaFonsecaPC,etal.(2008)JBiolChem283,23305–23314.5.KimHM,etal.(2011)BiochimBiophysicaActa1809(2),67–79.
Coomassie-stainedSDS-PAGE
Lane1:MolecularweightmarkersLane2:5µgpurifiedBovine19S(PA700)

Coomassie-stainednative-PAGE
Lane1:5µgpurifiedBovine19S(PA700)

Activationof5nM20Sproteasome(Cat.#A1400)by25nMPA700,theproteasomeactivitywasassayedbyusing50µMSuc-LLVY-AMC(Cat.#G1100)asthesubstrate.TheAMCfluorescencewasmonitoredbyaplatereaderwithexcitationandemissionfiltersof360±40nmand460±30nm,respectively.
品牌介绍

泛素-蛋白酶体生物技术有限公司(UBPBio),LLC是一家私有公司,由科学家和投资人于2011年成立。UBPBio致力于为学术界和工业界提供高质量的试剂,以加快对泛素-蛋白酶体系统及相关途径的发现。 。目前,我们的产品线包括16个类别,提供350多种产品。如果您在泛素领域需要特殊试剂,请与我们联系,我们将竭诚为您服务。 

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